I thought I would try a nootropic, or “smart drug,” to see how it would work for me. I really like the podcast Smart Drug Smarts, by Jesse Lawler. It is well produced, informative and entertaining. Jesse is great, however, he does not shy away from pitching his products as in each episode he encourages you to buy his nootropic, Nexus.
Nexus ingredients include Aniracetam, CDP Choline, Phosphatidylserine, and Pycnogenol®. On the website the product claims to “enhance cognition, beat stress, and sharpen concentration.” It goes on to claim that it created with fast thinking and neuroprotectivity in mind. The capsules are not cheap. At $1.00 a capsule and a recommended daily dose of 2 capsules, you are in for $60 a month, or $55 if you subscribe. At that cost, it had better work.
Would Nexus improve my cognitive performance?
What I Did
I tested myself using eight cognitive tests in the Quantified-Mind app after either taking Nexus or not. I then compared scores of the group of tests where I took Nexus to the scores where I did not take Nexus to see if the smart drug improved my test scores.
How I Did It
I created a spreadsheet column of randomly assigned numbers between o and 1. Each day in the afternoon I checked the next number in the column. It if was 1, I took two caplets of Nexus. If it was 0, I did not take Nexus. Thirty minutes after I took the capsule (or not), I would open the Quantified-Mind app and take eight tests. Those tests took approximately 15 minutes. They ranged from memory tests like dual-n-back to attention and reaction tests. I took down each test score for all eight tests and put them in the spreadsheet. After 19 tests, I compared the averages in the two groups and did a student’s TTest to see if the differences in readings were significant.
What I Learned
Smart drugs do not make me smart. Of the eight tests I took during each session, there was no significant difference in the readings between if I had taken Nexus or I had not. Here are my scores:
You can see that none of the tests had a statistically significant difference. If there was, the TTest P value would have been less than .05. You can argue that the sample size was too small. If we discard the TTest and just look at the averages, my scores seemed to go down in all but two of the categories.
Of interest is that on one test I seemed to do better – Attentional Focus. On that test you stare at two lines and tap a key when one gets longer. It can be difficult to maintain staring at the lines and the Nexus seemed to improve my averages there. On all the others, where I had some cognitive task to perform, my scores seemed to be degraded.
So I guess if I had an important report to write and I took Nexus I would stay focussed on the keyboard and keep typing, but the words that came out might not make as much sense.
One of the things I learned from Smart Drug Smarts podcast is that a test of one brain…is a test of one brain. The mixture found in Nexus might work for you. And I will continue being a fan of Jesse and his podcast. It is intelligent, fun, and informative. I just won’t buy his nootropics because they don’t work for me.
One thing I did learn in several sessions I had to throw out is that a lack of sleep trashes cognitive performance. On those days that I had had a poor night sleep the night before my scores were awful. I threw out those sessions, and I learned that sleep trumps nootropics with respect to performance. So in the future if I get a good nights sleep, and have an inexpensive cup of coffee in the morning my brain will be in good enough shape to handle that work report without having to resort to smart drugs.